Vista Center Health Library
The Health Library at Vista Center is dedicated to providing accessible health information and resources to help people with vision loss understand their conditions and keep abreast of new treatments and research findings. We also provide custom information about health and vision loss in a downloadable word document format upon request.
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Combined cataract surgery with iStent inject reduces medication burden in glaucoma
Key Takeaways High pressure in the eye (intraocular pressure, or IOP) can lead to glaucoma, and reducing IOP is the primary treatment for glaucoma. The iStent inject (Glauckos), a tiny device that can be implanted into the eye during cataract surgery, was designed to increase fluid outflow from the eye, thereby reducing IOP. Jennifer C. Fan Gaskin, MD, […]
Nicox announces recruitment of last patient in US in Denali Phase 3 trial of NCX 470
Key Takeaways Abnormally high pressure in the eye (elevated intraocular pressure, IOP) is regarded as one of the most important risk factors for developing glaucoma. NCX 470 is a novel eye drop that includes two complementary activities in a single molecule to combat high IOP. In a news release, Nicox SA announced the recruitment and randomization of the […]
Five year results of the Glaucoma Intensive Treatment Study (GITS)
Key Takeaways Most patients with glaucoma are offered intraocular pressure (IOP)-lowering treatment immediately after diagnosis. The most common and recommended approach when initiating glaucoma treatment is to set a target IOP and to adjust treatment until this IOP level is reached. Once the target IOP has been reached, the patient is followed with tonometry (test […]
Novel implants show promise in drug delivery
Key Takeaways Drug-eluting implants in various stages of study and approval may provide efficient, sustained drug delivery, overcoming barriers to penetration, according to a presentation at Kiawah Eye by Neel R. Desai, MD. “Only 0.001% of a topical drug is thought to be accessing the retina, and 5% accesses the anterior segment [front third of […]
Study examines nanodrug for optic nerve recovery
Key Takeaways In a press release, NurExone Biologic Inc announced the preliminary results from a small study exploring the use of its flagship nanodrug, ExoPTEN, for optic nerve recovery in a rat model. The study was initiated by Michael Belkin, MD, from Tel Aviv University’s Goldschleger Eye Research Institute, after ExoPTEN demonstrated nerve regeneration after spinal […]
Gene therapy discovery triggers hope for glaucoma patients
Key Takeaways The protein tau is essential to the function of cells in the brain and central nervous system, but when overproduced under certain conditions, it forms tangles that clog the cells’ internal structures. These tangles have also been found in Alzheimer’s disease patients. Tau is also present in neuronal cells in the retina, and […]
Key mechanism of intraocular pressure regulation suggests novel treatment approaches for glaucoma
Key Takeaways In many glaucoma patients, the fluid within the eye (known as “aqueous humor”) builds up, resulting in higher intraocular pressure (IOP, the amount of pressure or force inside of your eyes). Long-term medication is required to control high IOP. However, current drugs have limitations in that they can only slow glaucoma progression rather than halt […]
Statin use linked to higher risk of glaucoma
Key Takeaways Statin use was associated with a higher likelihood of glaucoma in adults with hyperlipidemia (an excess of fats or lipids in the blood), even those whose “bad” cholesterol was at optimal levels, according to a study of over 79,000 patients ages 40 and older in the All of Us (AoU) Research Program. The results were reported by […]
ChatGPT may have a future use in glaucoma
Key Takeaways Large language models (LLMs) such as ChatGPT show great promise in the realm of glaucoma with additional capabilities of self-correction, a recent study published in the journal Frontiers in Medicine found. However, use of the technology in glaucoma is still in its infancy, and further research and validation are needed, according to first author Darren […]
Sozinibercept combination therapy shows durability in patients with diabetic macular edema
Key Takeaways VEGF inhibitors are drugs that block the activity of vascular endothelial growth factor, a signal protein produced by cells that stimulates the formation of blood vessels. Most VEGF inhibitors used in the treatment of diabetic macular edema (DME) only block the activity of a VEGF family member called VEGF-A. Sozinibercept (OPT-302) is a drug that blocks […]
Disclaimer: Reports are excerpted/edited unless otherwise noted. Medical definitions are provided via Google/medical dictionaries. This project is done as a courtesy to the blind and visually impaired community. We do not recommend any particular treatment. Our Material might not represent all that is available on the subject. This information might not apply specifically to your own condition. Our material is not intended as a substitute for medical care. Our material should be used to formulate questions for discussion with your physician. We hope that the information you find at The Health Library will be useful in communicating with your health professionals. If you have any questions about your unique medical condition, we strongly advise that you see your physician.
The Health Library at Vista Center is maintained by Miriam Kaplan, PhD, Editor-in-Chief and Coordinator, and Dawn Wilcox BSN RN, Associate Editor. The Health Library at Vista Center is an affiliate of the Stanford Hospital Health Library.